• API Gliclazide Ep CAS 21187-98-4
  • API Gliclazide Ep CAS 21187-98-4
  • API Gliclazide Ep CAS 21187-98-4
  • API Gliclazide Ep CAS 21187-98-4
  • API Gliclazide Ep CAS 21187-98-4
  • API Gliclazide Ep CAS 21187-98-4

API Gliclazide Ep CAS 21187-98-4

Powder: Yes
Customized: Non-Customized
Certification: ISO 9001
Suitable for: Adult
State: Solid
Purity: >99%
Samples:
US$ 100/Piece 1 Piece(Min.Order)
| Request Sample
Customization:
Diamond Member Since 2019

Suppliers with verified business licenses

Shandong, China
  • Overview
  • Product Description
  • Application
  • Packaging & Shipping
  • Company Profile
  • FAQ
Overview

Basic Info.

Model NO.
API
Transport Package
25kg/Drum
Specification
EP
Trademark
SCM Pioneering
Origin
China
HS Code
29
Production Capacity
5000kgs/Month

Product Description

API Gliclazide Ep CAS 21187-98-4

API Gliclazide Ep CAS 21187-98-4

 

Product Description

Gliclazide, molecular formula C15H21N3O3S, is a sulfonylurea oral anti diabetes drug. It is white crystal or crystalline powder, odorless, tasteless, and used to treat type II diabetes, and β Cell sulfonylurea receptor (SUR1) binds and further blocks ATP sensitive potassium channels. Therefore, the outflow of potassium is significantly reduced, resulting in β Cell depolarization. then, β Voltage dependent calcium channels in cells open, leading to the activation of calmodulin, which leads to exocytosis containing in-sulin secretion granules. It can also effectively improve the antioxidant status and nitric- oxide mediated vasodilation in patients with type 2 diabetes, and protect the pancreas β Cells are protected from hydr ogen peroxide damage.
API Gliclazide Ep CAS 21187-98-4

Test Specifications Results of analysis
Appearance White or almost white powder White powder

Solubility
Practically insoluble in water, fieely soluble in methy lene chloride; Sparinglysolubleinacetoneslght lysolublinethanol96percent)
Meets the requirements

Identifications
The  nfred  bsorpn  petum  sconcordnt  wih  ha obaned
with gliclazide CRS.

Meets the requirements
Impurity B(By HPLC) ≤2ppm 0.2ppm
Related substances
(By HPLC)
Impurity F≤0.15% Non-detected
Each unspecified impurity ≤0.10% 0.04%
Sum of impurities other than F≤0.2% 0.06%
Loss on drying ≤0.25% 0.06%
Sulfated ash ≤0.1% 0.02%
Residual solvents (By GC) Ethylacetate NMT 2500 ppm 257ppm
N,N-Dimethyl formamide NMT880 ppm Non-detected
Assay 99.0-101.0%.on dried basis. 99.4%
Conclusion The test results conform with BP2019
 

Application

Gliclazide is used to treat type 2 diabetes. Type 2 diabetes is an illness where the body does not make enough insuli n, or the insuli n that's made does not work properly. This causes high blood sugar (hyperglycaemia). Gliclazide lowers your blood sugar by increasing the amount of insuli n your body produces.

API Gliclazide Ep CAS 21187-98-4

API Gliclazide Ep CAS 21187-98-4

 

Packaging & Shipping

Package

 25kg cardboard drums with inner 1kg/Alumnium Foil Bag or as otherwise agreed upon.

Storage

Store in a dark and closed place in a dry place.

API Gliclazide Ep CAS 21187-98-4

 

Company Profile

SCM Pioneering Co., Ltd is an emerging supplier of high quality ingredients which based in Shandong province, China.

SCM was established by group of experts who have more than ten years experiences in pharmaceutical and food ingredients industries. with our deep knowledge and diligence, together with our associated plants, we would like to provide one-stop sourcing solutions for customers, to save your time and secure your purchasing.

API Gliclazide Ep CAS 21187-98-4

 

FAQ

1. What symptoms does Gliclazide apply to?

It is mainly used for mild and medium-sized diabetes with no ketosis tendency and with no effect on diet control alone after the onset of adulthood. It can also improve the fundus lesions, metabolism and vascular function disorders of diabetic patients. It can be used in combination with biguanide oral hypoglycemic drugs for patients who cannot be controlled by single use, and can reduce the amount of in-sulin used in combination with in-sulin to treat in-sulin dependent diabetes.

2.Which filed can be used for?
Well, it is widely used in Pharmaceuticals,Treat diabetes and reduce blood sugar.

3.Can I get some sample for test?
Sure, we can supply samples free for your test. Normally 20g is enough.

4.How can you guarantee the quality?
We have regular factory inspection to view the production status. And compare all qualified batches to select the best one for our customer before delivery.

5.When can you deliver goods if we confirm the order?
We will arrange the latest production batch for you, within seven days.

 

Dear friends, now contact us to get more benefit!

 

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Diamond Member Since 2019

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Management System Certification
ISO 9001, ISO 14001, ISO 22000